# Pro Evolve BioPharma Commercial Strategy Prompt Pack **Prototype demo:** HealthFounderOS by PredictCare.AI **Buyer persona:** BioPharma CEO **Use case:** Convert a pharma strategy deck into a governed Commercial Strategy Plan integrating marketing, sales alignment, Direct-to-Consumer (DTC), and Direct-to-Physician (DTP) activation. **Important guardrail:** Do not paste PHI, patient-level data, non-public trial data, confidential legal advice, or unreleased regulated claims into public or unmanaged AI tools. --- ## Primary framework spine This demo uses exactly **three primary frameworks**. Everything else is evidence, technique, or commentary. 1. **ExO 3.0 = the destination** MTP + DRIVE, the intelligence engine, + SHAPE, the organizational form. 2. **Intelligence Stack = the new operating system** Six cognitive layers plus a GOVERN/ASSURE control plane. John Boyd’s OODA loop scaled into organizational architecture. 3. **REWRITE = the playbook** Six sequenced steps from current state to ExO 3.0. --- ## How to use this pack 1. Start with the deck audit prompt. 2. Convert the deck into a CEO-facing commercial strategy thesis. 3. Align marketing, sales, DTC, and DTP activation. 4. Map claims, evidence, approvals, and launch-phase boundaries. 5. Use the Intelligence Stack to define the operating system. 6. Use REWRITE to sequence the transition from current state to ExO 3.0. 7. Export the final Commercial Strategy Plan as a PDF for executive review. --- ## Prompt 1 — BioPharma Commercial Deck Audit ```text You are a healthcare commercial strategy operator auditing a BioPharma commercial strategy deck for a CEO. Review the deck content below and produce a concise executive audit with: 1. Core commercial thesis 2. Target audiences and stakeholder map 3. Marketing strategy assumptions 4. Sales / field alignment assumptions 5. Direct-to-Consumer (DTC) activation opportunities and constraints 6. Direct-to-Physician (DTP) activation opportunities and constraints 7. Evidence base and missing proof 8. Message hierarchy 9. Launch-stage readiness 10. Compliance / MLR / legal review flags 11. Recommended CEO decisions and next-best actions Rules: - Do not invent data. - Separate facts from assumptions. - Flag claims that require medical, legal, regulatory, compliance, or MLR review. - Respect pre-launch vs legally approved commercial launch boundaries. - Keep the tone respectful and CEO-ready. Deck content: [PASTE EXTRACTED DECK TEXT HERE] ``` --- ## Prompt 2 — ExO 3.0 Destination ```text Turn the deck audit into an ExO 3.0 destination statement for a BioPharma CEO. Use exactly these components: - MTP: the mission-level commercial purpose - DRIVE: the intelligence engine for sensing, deciding, learning, and improving execution - SHAPE: the organizational form required to align marketing, sales, DTC, DTP, medical, legal, and leadership Output: 1. One-sentence destination 2. MTP draft 3. DRIVE requirements 4. SHAPE requirements 5. What must change from current state 6. CEO decision required Do not introduce additional primary frameworks. ``` --- ## Prompt 3 — Intelligence Stack Operating System ```text Design the Intelligence Stack for this commercial strategy. Use six cognitive layers plus a GOVERN/ASSURE control plane. Treat John Boyd's OODA loop as the operating logic scaled into organizational architecture. For each layer, define: - Purpose - Source inputs - AI-assisted work - Human decision rights - Outputs - Risks / controls Include layers for: 1. Sense market and stakeholder signals 2. Understand / interpret evidence and context 3. Orient strategy and priorities 4. Decide next-best commercial actions 5. Act through marketing, sales, DTC, and DTP workflows 6. Learn from outcomes and feedback 7. GOVERN/ASSURE control plane across claims, privacy, compliance, MLR, legal, and executive decision rights ``` --- ## Prompt 4 — REWRITE Playbook ```text Create a REWRITE transition plan from current-state deck strategy to ExO 3.0 commercial operating model. Use six sequenced steps. For each step include: - Objective - Current-state friction it addresses - Work to perform - Prompt / tool needed - Owner - Review gate - Output - CEO decision Keep the sequence practical for a small BioPharma commercial team. ``` --- ## Prompt 5 — Marketing + Sales Alignment ```text Convert the strategy into an aligned marketing and sales operating plan. Include: - Shared commercial thesis - Audience segments - Message hierarchy - Sales enablement needs - Field feedback loop - CRM / follow-up workflow - Content governance - Decision rights between marketing, sales, medical, legal, and CEO - Metrics that show alignment is improving Flag any place where disconnected sales, marketing silos, or lost organizational memory could cause drift. ``` --- ## Prompt 6 — DTC + DTP Activation Map ```text Create a DTC and DTP activation map for the commercial strategy. For each path, define: - Audience objective - Allowed education / messaging boundaries - Evidence needed - Funnel or engagement workflow - Hand-off to sales/field/medical where appropriate - Approval requirements - Risks and safer alternatives - Metrics Do not make patient targeting, medical advice, clinical decision support, or unapproved claim recommendations. ``` --- ## Prompt 7 — Claims & Evidence Matrix ```text Build a claims and evidence matrix from the deck. Columns: 1. Proposed claim or message 2. Intended audience: CEO / HCP / Patient / Payer / Field / Internal 3. Supporting evidence cited in the deck 4. Evidence gaps 5. Risk level: Low / Medium / High 6. Required reviewer: Medical / Legal / Regulatory / Compliance / MLR / Commercial 7. Safer alternative wording 8. Decision needed Do not approve claims. Flag review needs only. ``` --- ## Prompt 8 — Final Commercial Strategy Plan PDF ```text Convert the completed work into a CEO-ready BioPharma Commercial Strategy Plan that can be printed as a PDF. Structure: 1. Executive summary 2. Commercial thesis 3. ExO 3.0 destination 4. Intelligence Stack operating model 5. REWRITE transition plan 6. Marketing and sales alignment plan 7. DTC / DTP activation map 8. Claims and evidence review matrix 9. Governance, approvals, and launch-phase boundaries 10. 90-day implementation plan 11. Decision log 12. Risks and open questions 13. Next step recommendation Tone: clear, respectful, commercially sharp, compliance-aware. Do not overclaim. ```